Yes, it’s possible, but you typically must be in the U.S. in lawful status e.g., on a valid visa when you apply.

 After your spouse becomes a U.S. citizen, your case can speed up then you’d be an “immediate relative” and may adjust status more easily.

 If you’re outside the U.S., you can go through consular processing once your I-130 petition is approved and your priority date is current.

 If you’re in removal (deportation) proceedings, you can sometimes ask the court to pause or terminate your case once your petition is approved.